Insights into the molecular mechanism of replication fork rescue by RuvAB and the putative role of the bacterial RuvB-like protein RarA and its human homologue WRNIP1

The RuvAB(C) proteins promote branch migration and resolution of Holliday junctions (HJs) which form during homologous recombination and upon reversal of stalled replication forks. In addition to the function of RuvAB to process HJs formed at stalled forks, RuvAB have recently been shown to be requi...

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Bibliographic Details
Main Author: Bradley, A. S.
Published: University College London (University of London) 2009
Subjects:
570
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.625210