3q amplification in preinvasive lesions of the bronchial epithelium

3q amplification is the most common genomic aberration in squamous lung cancer, suggesting that a ‘driver’ oncogene for squamous lung cancer resides within the 3q amplicon. Studying preinvasive disease has the theoretical advantage of identifying the key early molecular events in the pathogenesis of...

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Bibliographic Details
Main Author: McCaughan, F.
Published: University College London (University of London) 2009
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.625264