The function and role of F2R polymorphisms in fibroproliferative lung disease
BACKGROUND: Activation of the coagulation factor II (thrombin) receptor, F2R, by coagulation proteinases contributes to lung inflammation and fibrosis following lung injury. F2R gene expression is raised in fibroproliferative lung disease and F2R-deficient mice are protected in a model of lung infla...
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University College London (University of London)
2010
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.625316 |