The function and role of F2R polymorphisms in fibroproliferative lung disease

The function and role of F2R polymorphisms in fibroproliferative lung disease

BACKGROUND: Activation of the coagulation factor II (thrombin) receptor, F2R, by coagulation proteinases contributes to lung inflammation and fibrosis following lung injury. F2R gene expression is raised in fibroproliferative lung disease and F2R-deficient mice are protected in a model of lung infla...

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Bibliographic Details
Main Author:	Lawson, P. J.
Published:	University College London (University of London) 2010
Subjects:	610
Online Access:	http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.625316

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