Interactions of host restriction factors with retroviral capsid proteins
Restriction factors interfere with retroviral infection, blocking the viral life cycle after cell entry, but prior to integration into the chromosomal DNA. Fv1 restricts murine leukaemia virus (MLV), whereas TRIM5α (T5) restricts human immunodeficiency virus (HIV), and other retroviruses. The mechan...
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University College London (University of London)
2010
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.625391 |