β-amyloid induced oxidative stress and its effects on astrocytes and neurons
Alzheimer’s disease (AD) is the most common form of dementia. It is characterized by the accumulation of amyloid plaques in the brain, made of β- amyloid (Aβ) fragments which activate NADPH oxidase expressed in astrocytes and microglia, increasing the rate of production of reactive oxygen species (R...
| Main Author: | |
|---|---|
| Published: |
University College London (University of London)
2011
|
| Subjects: | |
| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.625612 |