Defining the use of anti-PrP monoclonal antibodies in a mouse model of prion disease

Despite intense scientific scrutiny since the outbreak of variant Creutzfeldt-Jakob disease (vCJD) in the mid-1990s, no effective treatment is available for human prion disease. The passive transfer of anti-PrP monoclonal antibodies (mAbs) in prion-infected mice has been demonstrated to extend the m...

Full description

Bibliographic Details
Main Author: Carswell, C.
Published: University College London (University of London) 2011
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.625641