Investigating the roles of Notch signalling during inner ear development : new insights into the dynamics of Notch activity and the functions of Delta1

The Notch signalling pathway has ubiquitous roles during inner ear development. An early phase of Notch activity, via the ligand Serrate 1 mediates lateral induction and promotes the early formation of inner ear sensory patches. In addition, Notch signalling mediated by the ligand Delta1 regulates o...

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Bibliographic Details
Main Author: Chrysostomou, E.
Published: University College London (University of London) 2012
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.625827