The Breast Cancer, Early Disease: Toxicity from Therapy with Epirubicin Regimens – Cardiac Assessment and Risk Evaluation (BETTER-CARE) Study : design, set-up and analysis of a prospective multicentre collaboration to investigate the pharmacogenetics of anthracycline cardiotoxicity, using cardiovascular magnetic resonance imaging
Anthracyclines are highly effective chemotherapy drugs. However, their use is associated with anthracycline cardiotoxicity (AC), which may result in premature heart failure. Risk of AC is related to cumulative dose, but is also highly idiosyncratic. Effective tests to predict susceptibility are lack...
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University College London (University of London)
2013
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.626031 |