Rational design of enterokinase for the development of enhanced biopharmaceutical proteins

Enterokinase (EK) is a serine protease used to cleave therapeutic recombinant proteins during downstream processing. It has been selected for the activation and cleavage of a range of proprietary fusion proteins developed by Syntaxin Ltd. Whilst EK is well suited to this role in regards to substrate...

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Bibliographic Details
Main Author: Pradhan, S.
Published: University College London (University of London) 2013
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.626037