The discovery and evaluation of inhibitors of the KEAP1-NRF2 protein-protein interaction

Disruption of the interaction between the ubiquitination facilitator protein Keap1 and the transcription factor Nrf2 is a potential strategy for enhancing the expression of antioxidant and detoxification gene products that are regulated by this cap ‘n’ collar basic-region leucine zipper transcriptio...

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Bibliographic Details
Main Author: Hancock, R. M.
Published: University College London (University of London) 2013
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.626046