The role of regulators of G-protein signalling (RGS) in the predisposition to atrial fibrillation
The electrophysiological basis of atrial fibrillation (AF) is unknown. Regulators of G-protein signalling (RGS) act to deactivate G-protein signalling; they interact with the α subunit and accelerate intrinsic GTP-ase activity. RGS 4 negatively regulates inhibitory Gαi/o and Gαq/11 signalling. Absen...
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University College London (University of London)
2013
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.626053 |