Investigation of unique dependencies of cells lacking the PTEN tumour suppressor gene

Over the past ten years significant effort has been put in the identification of pharmacological targets that facilitate the selective targeting of cancer cells. The concept of synthetic lethality in combination with RNA interference (RNAi) technology provides an attractive platform for the identifi...

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Bibliographic Details
Main Author: Vlachogiannis, G.
Published: University College London (University of London) 2013
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.626194