Loss of Rb co-operates with Ras to drive biogenesis in mammalian cells
The p53, Rb and Ras/PI3K pathways are implicated in the development of the majority of human cancers. A number of studies have established that these pathways co-operate at the level of the cell cycle leading to loss of normal proliferative controls. For this thesis I have investigated how these sig...
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University College London (University of London)
2013
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.626367 |