Novel signalling pathways in myocardial conditioning against reperfusion injury
Ischaemic preconditioning (IPC) and insulin protect the heart against lethal ischaemia-reperfusion (IR) by activating cardioprotective kinases such as PI3K-AKT. This thesis explores the effect of endothelial dysfunction, as seen in diabetes - a major risk factor for ischaemic heart disease, on IPC u...
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University College London (University of London)
2013
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.626371 |