Comparative analysis of interactions of the RASSF family mediated by the Ras-association (RA) and SARAH domains

Members of the RASSF family (RASSF1-10) have been identified as candidate tumour suppressors that are frequently downregulated by promoter hypermethylation in cancers. These adaptor proteins carry a common Ras-association (RA) and SARAH domain (RASSF1-6) that can potentially bind Ras oncoproteins an...

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Bibliographic Details
Main Author: Chan, J. J.
Published: University College London (University of London) 2013
Subjects:
570
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.626451