Structural folding dynamics of an archetypal conformational disease using Nuclear Magnetic Resonance Spectroscopy
Members of the serpin (serine protease inhibitor) superfamily of proteins regulate key physiological processes through their ability to undergo major conformational transitions. In conformational diseases, native protein conformers convert to pathological species that polymerise. Structural characte...
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University College London (University of London)
2014
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.626602 |