The role of MTOR pathway and growth factors as revealed by gene expression profiling in diffuse congenital hyperinsulinism

Congenital hyperinsulinism (CHI) is the commonest cause of recurrent and persistent hypoglycaemia in infants. Histologically there are two distinct types: focal and diffuse. The medical therapy for diffuse CHI involves diazoxide, glucagon and octreotide. The patients who are unresponsive to medical...

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Bibliographic Details
Main Author: Karuppanan Senniappan, S.
Published: University College London (University of London) 2014
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.626703