Creating site-specific abasic sites in the genome of Saccharomyces cerevisiae to analyse replication-associated lesion bypass
Abasic sites are thought to be one of the most frequently formed lesions within cells. They are particularly dangerous during DNA replication as they can block the progression of replication forks. Such stalled forks have the potential to collapse, which can impact genome stability and therefore cel...
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University College London (University of London)
2014
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.626800 |