Statistical modelling of mitochondrial disease
Mitochondrial DNA mutations are a major cause of disease in the human population. Understanding the disease associated with these mutations is complicated by heteroplasmy, the mixture of wild-type and mutated mitochondrial DNA. Heteroplasmy can vary between cells, tissues, and organs, and the diseas...
Main Author: | Grady, John Patrick |
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Published: |
University of Newcastle upon Tyne
2014
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Subjects: | |
Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.627702 |
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