The regulation of the hepcidin by modulators of the bone morphogenetic protein (BMP) pathway
Hepcidin, the iron regulatory peptide, has emerged as the master regulator of systemic iron homeostasis. Under normal circumstances, hepcidin expression is upregulated by excess iron and inflammation; and downregulated by iron deficiency, anaemia and hypoxia. Insights gained into the pathogenesis of...
Main Author: | |
---|---|
Published: |
King's College London (University of London)
2012
|
Subjects: | |
Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.628078 |