Regulation of APOBEC3 activity and HIV-1 replication by P-body associated proteins

The APOPEC3 family of cytidine deaminases play an important role in host mediated antiviral defence against retroelements, including HIV-1. Although much has been discerned regarding the anti-viral nature of these proteins, their cellular function, as well as mechanisms of functional regulation and...

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Bibliographic Details
Main Author: Phalora, Prabhjeet
Published: King's College London (University of London) 2012
Subjects:
612
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.628091