Cationic lipid formaulation of short interference RNA (siRNA) for delivery to respiratory epithelial cells

Cationic lipids are commonly used and relatively safe vectors for plasmid (pDNA) delivery. In search for an optimal lipid-based formulation for siRNA delivery to the lungs, cationic lipid-based carriers were investigated for the delivery of siRNA in comparison with pDNA delivery. The aim was to dete...

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Bibliographic Details
Main Author: Betkaoui, Radia
Published: King's College London (University of London) 2012
Subjects:
611
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.628115