The development of a humanised mouse model of ANCA associated vasculitis
Anti-neutrophil cytoplasmic autoantibodies (ANCA), targeting the neutrophil protein granules myeloperoxidase (MPO) and proteinase 3 (PR3), activate neutrophils in vitro, and are associated with a systemic autoimmune vasculitis, in which a pauci-immune crescentic glomerulonephritis is common. The in...
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King's College London (University of London)
2013
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.628344 |