Indirect analysis of oligonucleotides using cleavable small molecule mass tags with detection by mass spectrometry

In the 1990s, siRNAs and microRNAs were discovered to be naturally occurring genetic regulators. This provided a new potential mechanism of action for drugs with applicability to a wide range of therapeutic areas. Consequently, a substantial increase into oligonucleotide research has occurred, leadi...

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Bibliographic Details
Main Author: Riley, Jo-Anne
Other Authors: Langley, Graham
Published: University of Southampton 2013
Subjects:
540
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.628660