The synthesis of fluorinated carbohydrates and fluorinated cyclohexanols

Carbohydrates are central to many fundamental processes. However, their interactions to proteins are characterized by low binding affinity. An attractive strategy to improve this affinity is polyfluorination of carbohydrates. This thesis describes the synthesis and extensive NMR characterisation of...

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Bibliographic Details
Main Author: Mtashobya, Lewis
Other Authors: Linclau, Bruno
Published: University of Southampton 2014
Subjects:
540
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.628741