Understanding the "rules of engagement" for membrane protein folding : chemical biology and computational approaches for determination of structure and dynamics

Approximately one third of genes in the human genome (1) encode transmembrane (TM) proteins and form more than half of all drug targets (2). However, our understanding of how these proteins fold into their functional form, as well as how they may misfold into a disease-associated form, remains a dif...

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Bibliographic Details
Main Author: Nash, Anthony
Published: University of Warwick 2014
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.629108