The isolation and characterisation of MHC-presented peptides from CML-derived cell-lines, with a focus on post-translational modification

Phosphorylation is a key regulator of protein function and activity, and aberrant kinase activity is implicated in a wide range of malignancies, of which the bcr:abl fusion kinase found in chronic myeloid leukaemia is a classic example. As phosphopeptides are known to be presented by both the MHC cl...

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Bibliographic Details
Main Author: Kapoor, K. N.
Published: Nottingham Trent University 2011
Subjects:
612
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.629238