The isolation and characterisation of MHC-presented peptides from CML-derived cell-lines, with a focus on post-translational modification
Phosphorylation is a key regulator of protein function and activity, and aberrant kinase activity is implicated in a wide range of malignancies, of which the bcr:abl fusion kinase found in chronic myeloid leukaemia is a classic example. As phosphopeptides are known to be presented by both the MHC cl...
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Nottingham Trent University
2011
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.629238 |