Functional interactions between peroxisome proliferator-activated receptor-gamma and polipoprotein E isoforms in the regulation of neural functions in models of insulin resistance-relevance to Alzheimer's disease
Insulin resistance, part of the metabolic syndrome, is associated with type 2 diabetes mellitus (T2DM) and increased risk for Alzheimer’s disease (AD). The e4 allele of APOE is the greatest genetic risk factor for sporadic, late onset AD, and is also associated with risk for T2DM. The thiazolidinedi...
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King's College London (University of London)
2012
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.631279 |