The use of epidermal growth factor receptor activity biosensing to understand cancer gene network sensitivity and to monitor intratumoural heterogeneity

The epidermal growth factor receptor (EGFR) plays a pivotal role in cellular proliferation, differentiation and migration and is found to be overexpressed in a variety of tumours including the basal-like subtype of breast cancer. Despite decades of basic research in the HER signalling field, and man...

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Bibliographic Details
Main Author: Cheung, Anthony
Published: King's College London (University of London) 2013
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.631326