The development of a HIV vector system to explore drug susceptibility and fitness of clinical isolates

Following the identification of a highly resistant protease containing a novel insertion (35QN), together with a series of additional gag mutations. We wished to explore the gag-protease interrelationships, and associated replication capacity deficit/compensation. A replication competent NL4-3 based...

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Bibliographic Details
Main Author: Kohli, A.
Published: University College London (University of London) 2008
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.631777