Characterisation of the essential t⁶A tRNA modification enzymes and evaluation as a potential novel antimicrobial target

Modified bases in RNA molecules are common, with over one-hundred individual modifications reported to date. In transfer RNA (tRNA), these modifications help hold the molecule in its proper conformation, allow the aminoacyl-synthetases to attach the amino acid to the correct tRNA for transfer to the...

Full description

Bibliographic Details
Main Author: Cargill, James Stuart
Other Authors: Palmer, Tracy
Published: University of Dundee 2014
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.633757