Uniform linear poly(ethylenimine) via poly(oxazoline)s : synthesis, mechanism of toxicity and the role of the free polymer during transfection
Linear poly(ethylenimine) is the current “gold standard” gene transfection agent. It is synthesised via the cationic ring opening polymerisation of 2-ethyl-2-oxazoline followed by the acid catalysed hydrolysis to the hydrochloride salt. However the synthesis of the parent polymer produces a broad di...
| Main Author: | |
|---|---|
| Other Authors: | |
| Published: |
Imperial College London
2013
|
| Subjects: | |
| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.634088 |