The neuroprotective role of osteopontin in in-vitro and in-vivo models of Parkinson's disease
Osteopontin (OPN), a glycosylated phosphoprotein, is down regulated in remaining dopaminergic neurones in Parkinson’s disease. It has protective properties including anti-inflammatory and anti-apoptotic effects. Therefore, it was hypothesised that OPN treatment protects dopaminergic neurons from tox...
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King's College London (University of London)
2012
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.634178 |