A small molecule modulator of prion protein increases human mesenchymal stem cell lifespan, ex vivo expansion and engraftment to bone marrow in NOD/SCID mice
Human mesenchymal stem cells (hMSCs) have been shown to have potential in regenerative approaches in bone and blood. Most protocols rely on their in vitro expansion prior to clinical use. However, several groups including our own have shown that hMSC lose proliferation and differentiation ability wi...
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University of Sheffield
2014
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.634319 |