Applications of liquid chromatography-tandem mass spectrometry to cytochrome P450 inhibiton screening and the measurement of plasma free metanephrines
A more detailed knowledge of the inhibition profiles for new chemical entities with respect to the major cytochrome P450 enzymes is prerequisite for their registration. The use of recombinant P450 enzymes is intended to limit interactions with other minor P450 enzymes and their reductases that are p...
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Swansea University
2005
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.637086 |