The human cardiac ryanodine receptor gating behaviour : a study of mechanisms
Rhythmic contraction of cardiac myocytes is maintained by precisely controlled Ca2+ efflux from intracellular stores mediated by the cardiac ryanodine receptor (RyR2). Mutations in RyR2 result in perturbed Ca2+ release that can trigger arrhythmias. RyR2- dependent ventricular tachyarrhythmia is an i...
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Cardiff University
2014
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.637125 |