Molecular and cytogenetic analysis of premature ageing disease Hutchinson-Gilford Progeria Syndrome

The principal aim of this study was to evaluate the underlying cellular mechanisms causing HGPS by using an in depth cytogenetic and molecular approach. Firstly, the total genome karyotype of HGPS lines and clinically normal cell lines was analysed utilising modified, multi-colour fluorescent <i&...

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Bibliographic Details
Main Author: Seager, Anna L.
Published: Swansea University 2006
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.638787