Phospho-regulation of Lrg1 controls polarised growth in the human fungal pathogen Candida albicans
The small GTPase Rho1 is the positive regulatory subunit of β-1,3 glucan synthase, responsible for the main structural component of the cell wall. In turn Rho1 is negatively regulated by Lrg1, its GTPase activating protein (GAP). Here it is shown that a C. albicans lrg1ΔΔ mutant constitutively forms...
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University of Sheffield
2015
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.638968 |