Regulation of anaphase in mammalian meiosis

Missegregation of chromosomes during meiosis leads to formation of aneuploid eggs. Estimates suggest that in humans, about 10-30% of fertilised eggs and one-third of all miscarriages are aneuploid. Accurate chromosome segregation depends on the coordination between stepwise cohesion resolution and a...

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Bibliographic Details
Main Author: Rattani, Ahmed Anwer Ali
Published: University of Oxford 2012
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.639733