SFRP4 as an epigenetic biomarker of colorectal cancer risk

There is a lack of robust biomarkers of CRC risk. Epigenetic changes in the WNT-related SFRP4, a gene whose expression is down-regulated early in CRC development, may be a potential CRC risk biomarker. If SFRP4 promoter methylation proved to be a useful biomarker of CRC risk, it would have potential...

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Bibliographic Details
Main Author: Staley, Helen
Published: University of Newcastle upon Tyne 2014
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.639772