Genomic instability, deregulation of apoptosis and treatment responsiveness in sporadic colorectal cancer

Chromosomal instability was studied in 17 colorectal cancer cell lines using Spectral Karyotyping (SKY). RER-lines usually displayed extensive numerical and structural variations with marked heterogeneity. Most RER-lines showed a tendency to approach a near-triploid karyotype, and invariably had str...

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Bibliographic Details
Main Author: Abdel-Rahman, Wael Mohamed
Published: University of Edinburgh 2001
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.640122