Preparing and sequencing ultra-long DNA molecules from single chromosomes
In this thesis, I describe the development of a single-molecule platform for analysing long DNA molecules that captures haplotype and large-scale structural variation (SV) in addition to DNA sequence. Cunent DNA sequencing methods cannot adequately examine haplotype and SV - both contribute to biolo...
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University of Oxford
2013
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.640151 |