Investigation of the impact of MRP3 and MRP4 on the disposition of drugs and conjugates in rat and human
The importance of active drug transport in determining chemical fate is becoming increasingly clear, with efflux transporters such as MDR1, MRP2 and BCRP recognised as key determinants of drug action. The impact have been shown to impact compound bioavailability through first-pass effects; determine...
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University of Surrey
2015
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.640888 |