The expression of mammalian drug metabolising enzymes in S. cerevisiae

Adaptation to a chemically challenging environment is a critical aspect of the evolutionary process. As a result a wide variety of systems involved in xenobiotic metabolism have evolved. Two such systems are the phase I (drug toxification) Cytochrome P-450 monooxygenases and the phase II (drug detox...

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Bibliographic Details
Main Author: Black, Stephen M.
Published: University of Edinburgh 1990
Subjects:
579
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.641664