The role of the retinoblastoma gene in liver regeneration, polyploidisation and hepatocarcinogenesis
To determine the role of Rb in the regulation of hepatocyte replication, two models of liver regeneration were developed. The first involved the use of carbon tetrachloride, a liver-specific toxin, to cause necrosis. The second involved performing a partial hepatectomy (PH) – a surgical resection of...
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University of Edinburgh
2007
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.641835 |