Investigating the role of spindle checkpoint mutations in colorectal cancer

It has been hypothesised that mutations in genes involved in chromosome segregation and mitotic checkpoints may contribute to aneuploid phenotypes in colon tumours. In support of this hypothesis deletions and missense mutations in spindle checkpoint genes <i>BUB1</i> and <i>BUBR1&l...

Full description

Bibliographic Details
Main Author: Boyes, Laura
Published: University of Edinburgh 2004
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.641856