14-3-3 proteins and cholesterol-dependent membrane domains

In this thesis I set out to characterise the interaction of 14-3-3 with lipid raft-like membrane domains. 14-3-3 associated with DRMs isolated from rate brain extract in a 14-3-3 isoform specific manner. Inhibition of 14-3-3 target protein interactions suggested that this association was reliant on...

Full description

Bibliographic Details
Main Author: Brechin, C.
Published: University of Edinburgh 2007
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.641914