Inositol phosphorylceramide synthase of fungal sphingolipid biosynthesis : a potential target for selective agrochemical and therapeutic agents

The membrane-bound enzyme, inositol phosphorylceramide synthase (IPC synthase), encoded by <i>AUR1, </i>has been identified in yeast and fungi. Since IPC synthase is unique to fungi, there is an opportunity for development of a species-specific enzyme inhibitor that might have low toxici...

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Bibliographic Details
Main Author: Breen, Rachel S.
Published: University of Edinburgh 2005
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Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.641917