Identification of highly methylated human DNA sequences using a methyl-CpG binding domain column

A library of densely methylated sequences has been constructed from DNA derived from human blood. Genomic DNA was fractionated using a column which binds preferentially according to methyl-CpG density. The library contains known fragments of methylated CpG Islands (CGIs) and other novel regions with...

Full description

Bibliographic Details
Main Author: Brock, Graham J. R.
Published: University of Edinburgh 1997
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.641961